Swedish Researchers Create Groundbreaking '3-in-1' Antibody for Cancer Treatment
Stockholm, Sweden - Researchers at Uppsala University and KTH Royal Institute of Technology have made a significant breakthrough in cancer treatment, developing an antibody that combines three different functionalities to target and deliver a drug package while stimulating the immune system.
The "3-in-1 design" antibody is specifically tailored to identify and destroy cancer cells by delivering a unique tumour-specific material directly to immune cells and stimulating them simultaneously. This approach has shown promising results in both human blood samples and animal models, with mice receiving treatment experiencing prolonged survival and even complete remission from cancer at higher doses.
The researchers say that the advantages of this drug lie in its ease of production on a larger scale, while also allowing for easy tailoring to each patient's specific tumour. This customisation increases availability and accelerates the process from diagnosis to treatment.
"This is a major breakthrough in precision medicine for cancer, and we're excited to explore its potential benefits," said Sara Mangsbo, Professor at Uppsala University. "We believe that this treatment could be a game-changer in the fight against cancer."
The study's findings have implications for developing more flexible, faster, and safer treatments for cancer, which are currently limited. The researchers plan to use their fully optimised production process to manufacture the drug candidate for further safety studies and proceed with clinical trials in humans.
Meanwhile, on a separate international news development:
International Criminal Court Chief Prosecutor Faces Misconduct Probe
The Hague, Netherlands - The International Criminal Court has announced an external investigation into alleged misconduct by chief prosecutor Karim Khan, amidst reports of sexual misconduct. Khan has denied the allegations, stating that there was "no truth to suggestions" of such behaviour.
However, President of the Assembly of States Parties (ASP), Paivi Kaukoranta, said that an external probe is necessary to ensure a fully independent and impartial process. The investigation will assess whether Khan's actions during May's ICC decision led to any potential misconduct.
The International Criminal Court has not yet made its decision on seeking arrest warrants for Israeli Prime Minister Benjamin Netanyahu and former defence minister Yoav Gallant, or three top Hamas leaders, who are currently facing ICC prosecution for war crimes charges.