Pseudoconyza viscosa Exhibition Strong Antioxidant Potential Through Insilico Evaluation
A recent study published provisionally has shed light on the total phenolic and flavonoid content, as well as the in silico antioxidant evaluation of Pseudoconyza viscosa (Mill.), a medicinal plant widely used in food, cosmetic, and pharmaceutical industries.
According to the findings, Pseudoconyza viscosa (Mill.) displays substantial chemical composition, including 311.74 mg/g total phenolic content and 208.2 mg/g flavonoid, determined using high-pressure liquid chromatography (HPLC) and UV-visible spectroscopy. The ethanolic extracts of this plant have shown notable antioxidant potential through the application of molecular docking against human peroxiredoxin 5.
The researchers conducted in silico studies on major phenolic compounds of Pseudoconyza viscosa (Mill.), using Autodock Vina Software to determine their binding potential against human peroxiredoxin 5. The results suggest that dicaffeoylquinic acid has notable antioxidant properties, with a docking score of -7.8 against the mentioned protein.
In addition to in silico analysis, predictive models were employed to estimate ADME parameters and drug likeness characteristics of dicaffeoylquinic acid, demonstrating its potential as an antioxidant candidate comparable to synthetic drugs but without side effects.
The study's findings highlight the impressive therapeutic potential of Pseudoconyza viscosa (Mill.) warranting further investigation into its bioactive compounds for pharmaceutical and nutraceutical applications. Potential future studies should concentrate on exploring mechanisms of action and efficacy in clinical settings, paving the way for novel therapeutic agents derived from this medicinal plant.
This research provides significant insights into the use of herbal plants in medicine and their potential to develop novel antioxidant treatments.
Disclaimer: This news is subject to further verification once final version article is published.